The effects of whole body vibration and exercise on fibrinolysis in men

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dc.contributor.advisor Nagelkirk, Paul R.
dc.contributor.author Boyle, Leryn J. en_US
dc.date.accessioned 2011-06-09T15:32:19Z
dc.date.available 2011-06-09T15:32:19Z
dc.date.created 2009 en_US
dc.date.issued 2009
dc.identifier.uri http://cardinalscholar.bsu.edu/handle/123456789/193469
dc.description.abstract The purpose of this study was to examine the fibrinolytic response to whole body vibration (WBV) and exercise in men. Methods. Twenty healthy males (23.8 ± 4.2 years, 80.8 ± 3.3 kg·mˉ²) participated in the study. Each subject performed 3 trials in randomized order separated by 1 week. The trials consisted of exercise (X), vibration (V) and vibration + exercise (VX). Exercise sessions consisted of 15 minutes of unloaded squatting at a rate of 20 per minute. Vibration sessions were conducted on a WBV platform vibrating at a frequency of 30 Hz and amplitude of 1.5mm for 15 minutes. Plasma concentrations of active tPA and PAI-1 samples were assessed at baseline and immediately after each session. Results. tPA activity change from pre to post trial was found to be significantly greater in the VX condition (0.87 ± 0.35 IU·mlˉ¹ to 3.21 ± 1.06 IU·mlˉ¹) compared to the X (0.71 ± 0.36 IU·mlˉ¹ to 2.37 ± 1.13 IU·mlˉ¹) or V (0.83 ±0.25 IU·mlˉ¹ to 1.00 ± 0.37 IU·mlˉ¹) condition. tPA activity change from pre to post trial was found to be significantly greater in the X condition compared to the V condition. PAI-1 activity change from pre to post trial was found to be significantly decreased in the VX (6.54 ± 5.53 IU·mlˉ¹ to 4.89 ± 4.13 IU·mlˉ¹) and X (9.76 ± 8.19 IU·mlˉ¹ to 7.48 ± 7.11 IU·mlˉ¹) conditions compared to the V (5.68 ± 3.53 IU·mlˉ¹ to 5.84 ± 3.52 IU·mlˉ¹) condition. Heart rate change from pre to post exercise for the V condition (pre, 75 ± 8 bpm; post, 90 ± 7 bpm) was less than the change in the VX condition (pre, 77 ± 13 bpm; post, 148 ± 19 bpm) and X condition (pre, 71± 11 bpm; post, 139 ± 22 bpm). The change in heart rate was found to be similar in the X and VX conditions. Peak RPE was not significantly different between X and VX sessions. Conclusions. WBV does not stimulate increased fibrinolytic activity in young men. However, the significant increase in fibrinolytic potential observed during squatting exercise is enhanced by concurrent WBV.
dc.description.sponsorship School of Physical Education, Sport, and Exercise Science
dc.format.extent vi, 71 p. : digital, PDF file, ill. en_US
dc.source CardinalScholar 1.0 en_US
dc.subject.lcsh Vibration -- Physiological effect. en_US
dc.subject.lcsh Exercise -- Physiological aspects.
dc.subject.lcsh Fibrinolysis.
dc.subject.lcsh Men -- Physiology.
dc.title The effects of whole body vibration and exercise on fibrinolysis in men en_US
dc.description.degree Thesis (M.S.)
dc.identifier.cardcat-url http://liblink.bsu.edu/catkey/1493909 en_US


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  • Master's Theses [5318]
    Master's theses submitted to the Graduate School by Ball State University master's degree candidates in partial fulfillment of degree requirements.

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