An evaluation of regulatory T cell populations in orally tolerized and antibiotic-treated mice

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dc.contributor.advisor Bruns, Heather A.
dc.contributor.author Suer, Matthew T. en_US
dc.date.accessioned 2011-06-09T15:34:37Z
dc.date.available 2013-12-26T20:17:45Z
dc.date.created 2010 en_US
dc.date.issued 2010
dc.identifier.uri http://cardinalscholar.bsu.edu/handle/123456789/193702
dc.description.abstract The goal of the present study was to evaluate alterations to regulatory T cell (Treg) populations following antibiotic treatment. To examine this, we orally treated mice with Erythromycin and dissected the spleen and mesenteric lymph nodes. Tregs were isolated and enumerated by flow cytometry. Mice were then treated with OVA to induce oral tolerance, but tolerance could not be demonstrated. It was established that oral treatment with Erythromycin does not influence total CD4+ or Treg numbers.
dc.description.sponsorship Department of Biology
dc.format.extent 13 p. : digital, PDF file, col. ill. en_US
dc.source CardinalScholar 1.0 en_US
dc.subject.lcsh Erythromycin -- Physiological effect. en_US
dc.subject.lcsh T cells -- Effect of drugs on.
dc.subject.lcsh Immune response -- Regulation.
dc.title An evaluation of regulatory T cell populations in orally tolerized and antibiotic-treated mice en_US
dc.type Creative project (M.A.), 3 hrs. en_US
dc.description.degree Thesis (M.A.) en_US
dc.date.liftdate 2013-05-10 en_US
dc.identifier.cardcat-url http://liblink.bsu.edu/catkey/1578270 en_US


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  • Creative Projects [3230]
    Creative projects submitted to the Graduate School by Ball State University master's degree candidates in partial fulfillment of degree requirements.

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