Hemostatic adaptions following exercise training in patients with cancer

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dc.contributor.advisor Nagelkirk, Paul R.
dc.contributor.author Washburn, Ashley E.
dc.date.accessioned 2012-06-01T16:06:41Z
dc.date.available 2012-06-01T16:06:41Z
dc.date.created 2012-05-05
dc.date.issued 2012-05-05
dc.identifier.uri http://cardinalscholar.bsu.edu/handle/123456789/195958
dc.description.abstract Background: Thrombosis is a common and critical consequence of cancer. Changes in thrombotic potential were examined after exercise training in patients with cancer. Methods: Eight cancer patients (65 ± 11 yrs) completed this study, five exercising and three non-exercising controls. Venous blood samples were obtained at baseline and after approximately 12 weeks of study participation. Weekly physical activity was measured using a standard, validated physical activity questionnaire. APTT, PT, fibrinogen and factor VIII were measured before and after the 12-week intervention. Results: A time x group interaction trend (p=0.067) was observed for fibrinogen. Plasma concentrations decreased in the exercise group (355 ± 49.3 mg/dL to 331 ± 19.5 mg/dL), but increased in the control group (341 ± 52.4 mg/dL to 384 ± 107.9 mg/dL). Physical activity significantly decreased over time in both groups. Conclusions: Exercise training may reduce coagulation potential in cancer patients more than usual and customary care.
dc.description.sponsorship School of Physical Education, Sport, and Exercise Science
dc.subject.lcsh Thrombosis -- Prevention.
dc.subject.lcsh Exercise -- Physiological aspects.
dc.subject.lcsh Cancer -- Patients -- Physiology.
dc.subject.lcsh Cancer -- Complications.
dc.title Hemostatic adaptions following exercise training in patients with cancer en_US
dc.description.degree Thesis (M.S.)
dc.identifier.cardcat-url http://liblink.bsu.edu/catkey/1671230


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  • Master's Theses [5510]
    Master's theses submitted to the Graduate School by Ball State University master's degree candidates in partial fulfillment of degree requirements.

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