Abstract:
Aortic stiffness and cardiorespiratory fitness (CRF) are independent predictors of
cardiovascular disease (CVD), cardiovascular events, and early mortality and are known to be related
. However, the relationships between aortic stiffness and other cardiopulmonary
variables gathered during a maximal exercise test are largely unknown (CPET)
. PURPOSE: To examine the relationships between aortic stiffness and CPET
variables in apparently healthy adults. METHODS: Two hundred sixty-five subjects
performed a maximal cardiopulmonary exercise test to determine VO2max, Ventilatory
Threshold (VT), Oxygen Uptake Efficiency Slope (OUES), Exercise Circulatory Power (CP)
, Exercise Ventilatory Power (VP), VE/VCO2 slope, and Oxygen Pulse (O2 Pulse)
Aortic stiffness was measured via carotid-femoral pulse wave velocity (cfPWV). Data
were checked for normality, and pearson-product moment correlations were performed
to determine the associations between aortic stiffness and each CPET variable. Partial
correlations were run to adjust for age and gender. For group analysis, ANCOVAs were
to determine differences in CPET variables between PWV
RESULTS: V was associated with VO2max, VE/VCO2 slope,
VT, OUES, O2Pulse, CP, and VP. When adjusted for age and gender, VO2max (ml/kg/
min), VT, CP, and VP remained significant. B
CONCLUSION
2
raditional risk factors may help
clinicians detect subclinical disease and provide appropriate treatment.
