Transferable drug resistance among animal and human strains of Escherichia coli

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dc.contributor.advisor Hendrickson, Donald A. en_US Porter, Timothy E., 1943- en_US 2011-06-03T19:31:11Z 2011-06-03T19:31:11Z 1974 en_US 1974
dc.identifier LD2489.Z78 1974 .P67 en_US
dc.description.abstract This study was conducted to assess the incidence of infectious drug resistance among animal strains of Escherlchia coli. Fecal samples were examined from a cattle feedlot southeast of Muncie, Indiana. The use of tetracycline and sulfonamide compounds as feed additives was a common practice on this farm, and theoretically could provide the antibiotic pressure necessary to select for resistant strains. A total of 32 feedlot E. coli were isolated from the feedlot floor. In addition, 10 strains of E. coli isolated from patients with urinary tract infections were introduced into this investigation for comparative purposes. All isolates were tested for antibiotic susceptibility using disc-diffusion methods. Multiple resistant strains were designated as donor organisms and were used in conjugation experiments with an antibiotic sensitive recipient E. coli; wild type K-12 F-.Multiple drug resistance occurred among 21.8 percent of the feedlot E. coli isolated, with a predominance of resistance to chlorotetracycline, tetracycline, and sulfathiazole. Three out of seven multiple resistant donors isolated were able to transfer their antibiotic resistance markers to the recipient K-12 strain. Transferable drug resistance among the clinical isolates occurred in 6 of the 10 donor resistant strains, with tetracycline and ampicillin being the most frequently encountered resistance.Ball State UniversityMuncie, IN 47306 en_US
dc.format.extent vi, 41 leaves : ill. ; 28 cm. en_US
dc.source Virtual Press en_US
dc.subject.lcsh Escherichia coli. en_US
dc.subject.lcsh Drug resistance in microorganisms. en_US
dc.subject.other Ball State University. Thesis (M.S.) en_US
dc.title Transferable drug resistance among animal and human strains of Escherichia coli en_US Thesis (M.S.)--Ball State University, 1974. en_US
dc.identifier.cardcat-url en_US

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  • Master's Theses [5358]
    Master's theses submitted to the Graduate School by Ball State University master's degree candidates in partial fulfillment of degree requirements.

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