A spectroscopic study of tetracycline-metal binding sites

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dc.contributor.author Swinney, Stephen C. en_US
dc.date.accessioned 2011-06-03T19:37:53Z
dc.date.available 2011-06-03T19:37:53Z
dc.date.created 1987 en_US
dc.date.issued 1987
dc.identifier LD2489.Z9 1987 .S9 en_US
dc.identifier.uri http://cardinalscholar.bsu.edu/handle/handle/185897
dc.description.abstract The purpose of this investigation was to study the binding of divalent copper to tetracycline. This particular drug's ability to bind divalent metals is known to facilitate its biological activity. Ambiguities in several previous works as to the exact site of tetracycline-copper binding served impetus for this work.A novel method of approach was attempted in that the tetracycline was labelled with a free radical spin-probe in an attempt to increase the ability of various spectroscopic analyses to view the binding process. Infrared spectroscopy, ultraviolet spectroscopy, proton magnetic resonance, 13C magnetic resonance and electron spin resonance were the spectroscopic techniques that were used. en_US
dc.format.extent vi, 42 leaves : ill. ; 28 cm. en_US
dc.source Virtual Press en_US
dc.subject.lcsh Tetracycline. en_US
dc.title A spectroscopic study of tetracycline-metal binding sites en_US
dc.type Research paper (M.A.), 4 hrs. en_US
dc.description.degree Thesis (M.A.) en_US
dc.identifier.cardcat-url http://liblink.bsu.edu/catkey/500556 en_US

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  • Research Papers [5068]
    Research papers submitted to the Graduate School by Ball State University master's degree candidates in partial fulfillment of degree requirements.

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