Synthesis of 7-N-acetyldemethyllavendamycin cyclohexyl ester : an honors thesis (HONRS 499)

Cardinal Scholar

Show simple item record

dc.contributor.advisor Behforouz, Mohammad en_US Al-Anzi, Charmaine Heidi en_US 2011-06-06T18:23:31Z 2011-06-06T18:23:31Z 1993 en_US 1993
dc.identifier.other A-130 en_US
dc.description.abstract The goal of this research project is to synthesize 7- N -acetyldemethyllavendamycin cyclohexyl ester (5). Several analogs have previously been prepared by other researchers at Ball State University under the direction of Dr. Mohammad Behforouz. Lavendamycin analogs are of interest because some have exhibited potent inhibiting capabilities against rasK oncogenic cells.' At the present time there are no available drugs effective against tumors caused by ras K oncogenes.7- N-Acetyldemethyllavendamycin cyclohexyl ester will be synthesized and submitted to our collaborators at Eli Lilly and Company to be tested against oncogene cells. The anticancer activity of this compound will be compared with those of the analogs possessing straight chain ester residues in order to determine the effect of the cyclohexyl group on the anticancer activity.
dc.description.sponsorship Honors College
dc.format.extent 40 leaves : ill. ; 28 cm. en_US
dc.source Virtual Press en_US
dc.subject.lcsh Chemistry. en_US
dc.subject.lcsh Ball State University. Honors College -- Theses (B.?) -- 1993. en_US
dc.title Synthesis of 7-N-acetyldemethyllavendamycin cyclohexyl ester : an honors thesis (HONRS 499) en_US
dc.type Undergraduate senior honors thesis Thesis (B.?.)
dc.identifier.cardcat-url en_US

Files in this item

This item appears in the following Collection(s)

  • Undergraduate Honors Theses [5928]
    Honors theses submitted to the Honors College by Ball State University undergraduate students in partial fulfillment of degree requirements.

Show simple item record

Search Cardinal Scholar


My Account