This study explored the relationship between perceived familial support to self-esteem in gay and bisexual men along a continuum of infection with the AIDS virus. Subjects were primarily obtained from two HIV/AIDS care coordination, education and social support centers. All participants completed the Coopersmith (1967) Self-Esteem Inventory, the Perceived Social Support-Family (PSS-Fa) questionnaire by Procidano and Heller (1983) and a demographic questionnaire. Two hypotheses were proposed: 1) Self-esteem will increase with strength of perceived Perceived Familial Support familial support. 2) Self-esteem will decrease as the stage of HIV infection worsens. Significant support was found for the first hypothesis. The second hypothesis was not supported; however, some reasons are postulated. The continuum of HIV infection and self-esteem as it relates to stages of death and dying are discussed. Implications and suggestions for counseling HIV-infected persons are addressed.