Aortic stiffness and cardiopulmonary exercise test variables

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Remington, Hannah E.
Harber, Matthew P.
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Thesis (M.S.)
School of Kinesiology
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Aortic stiffness and cardiorespiratory fitness (CRF) are independent predictors of cardiovascular disease (CVD), cardiovascular events, and early mortality and are known to be related . However, the relationships between aortic stiffness and other cardiopulmonary variables gathered during a maximal exercise test are largely unknown (CPET) . PURPOSE: To examine the relationships between aortic stiffness and CPET variables in apparently healthy adults. METHODS: Two hundred sixty-five subjects performed a maximal cardiopulmonary exercise test to determine VO2max, Ventilatory Threshold (VT), Oxygen Uptake Efficiency Slope (OUES), Exercise Circulatory Power (CP) , Exercise Ventilatory Power (VP), VE/VCO2 slope, and Oxygen Pulse (O2 Pulse) Aortic stiffness was measured via carotid-femoral pulse wave velocity (cfPWV). Data were checked for normality, and pearson-product moment correlations were performed to determine the associations between aortic stiffness and each CPET variable. Partial correlations were run to adjust for age and gender. For group analysis, ANCOVAs were to determine differences in CPET variables between PWV RESULTS: V was associated with VO2max, VE/VCO2 slope, VT, OUES, O2Pulse, CP, and VP. When adjusted for age and gender, VO2max (ml/kg/ min), VT, CP, and VP remained significant. B CONCLUSION 2 raditional risk factors may help clinicians detect subclinical disease and provide appropriate treatment.