The following is a comprehensive study of male-female serial killer teams. The primary concern is to determine what factors influence the females' participation in such partnerships. This study begins by reviewing literature which discusses the differences between male and female serial killers. Then, the focus turns to male-female serial killer teams. Here, literature is again reviewed in order to explain the dynamics of these teams and the traits which are commonly found in the female members of these teams. This study closes with three case studies of some of the most infamous male-female serial killer teams: Charles Starkweather and Caril Ann Fugate, Paul Bernardo and Karla Homolka, and Alton Coleman and Debra Denise Brown. These case studies focus primarily on the female partners and the events which led to their participation in the murders.