Although the Massachusetts Youth Screening Instrument – Second Version (MAYSI-2) has been widely accepted as a short mental health screener in the juvenile justice system, its utility in predicting juvenile recidivism has not yet been explored. This study comprised of 424 subjects who have been detained at Allen County Juvenile Justice Center (ACJC) for criminal charges. Participant's MAYSI-2 total scores without the Alcohol/Drug Use subscale and Alcohol/Drug Use subscale scores were used to assess their utility in predicting juvenile recidivism. A correlational analysis using urinalysis results and Alcohol/Drug Use subscale scores suggested Alcohol/Drug Use subscale is an efficacious measure for assessing substance use among juvenile offenders. A multiple hierarchical regression and ROC analyses were conducted. Findings indicated that the MAYSI-2 total score and Alcohol/Drug Use subscale scores were not adequate predictors of recidivism. However, in exploratory analysis the Anger-Irritability subscale was found to be a significant predictor of juvenile recidivism.